ABSTRACT
Background: Coronavirus disease 2019 (COVID-19) infection has announced by the World Health Organization (WHO) as a pandemic disease in 2020. Identification and analysis of COVID-19 presentation are important for quick isolation and diagnosis. Respiratory symptoms are typically present in COVID-19 patients. Objectives: The objectives of this study were to identify of gastrointestinal (GI) symptoms and laboratory results in the initial presentation of COVID-19 patients. Materials and Methods: Our study is a retrospective study of 379 COVID-19 patients’ assessments. They were admitted into government hospitals in Kingdom of Saudi Arabia’s South and East regions through April month 2020. Results: About 14% of the patients were presented initially with GI symptoms only, in which Nausea and anorexia are the most common complain. The mean C-reactive protein, alanine aminotransferase , and aspartate aminotransferase levels were significantly elevated. Conclusion: It is crucial for physicians to be aware that COVID-19 infection could present initially with GI-related symptoms and keep appropriate attention and suspicion.